In studies, gynostemma has been shown to increase the time blood needs to clot. When it is taken with antiplatelet or anticoagulant drugs, the effect of the drug may be increased, resulting in uncontrolled bleeding.
- Antiplatelets include Plavix and Ticlid
- Anticoagulants include heparin and warfarin
Because it can enhance immune system function, gynostemma may interfere with the effects of drugs used to suppress the immune system after organ transplants or in other conditions. Taking gynostemma is not recommended for patients who take drugs such as:
- azathioprine (Imuran)
- cyclosporine (Neoral, Sandimmune)
Gynostemma can affect the ability of blood to clot after an injury. Aspirin can also delay clotting, so gynostemma should not be taken at the same time as aspirin.
Theoretically, if gynostemma is used with other herbs that affect blood clotting, bleeding may occur. Some of the most common herbal products that might inhibit blood clotting are:
- Devil’s Claw
- Ginger (in high amounts)
- Horse Chestnut
- Panax Ginseng
Some interactions between herbal products and medications can be more severe than others. The best way for you to avoid harmful interactions is to tell your doctor and/or pharmacist what medications you are currently taking, including any over-the-counter products, vitamins, and herbals. For specific information on how gynostemma interacts with drugs, other herbals, and foods and the severity of those interactions, please use our Drug Interactions Checker to check for possible interactions.