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Jiaogulan Side Effects, Simply Explained

June 02, 2018

Jiaogulan Side Effects, Simply Explained

Pregnant Women & Nursing Mothers

There is no available research that discusses how Jiaogulan might affect unborn babies and infants. Therefore, suggest to avoid drinking Jiaogulan while pregnant and while breast-feeding. It’s better to stay on the safe side.

Additionally, we suggest you hold off on giving your child Jiaogulan until he or she is in the later years of childhood. Although have been no documented negative Jiaogulan side effects in children, we cannot say with certainty that it is 100% safe for children do consume.

Jiaogulan Side Effects

Some people have reported Jiaogulan to cause nausea. In some cases, it has been described as significant. In addition, there have also been cases in which people experienced more frequent bowel movements.

However, aside from those two minor side effects, no other side effects have been reported consistently from using gynostemma.

It is important to note that very few studies of its use have been conducted in humans. Therefore, it is possible that there are unknown Jiaogulan side effects waiting to be discovered. If by chance you do experience unexplained side effects while taking Jiaogulan, then you should stop taking it and tell your doctor or pharmacist about the side effects.

Jiaogulan Interactions

It may be the case that you are taking multiple types medications at the same time. If so, then you always want to be aware of the potential interactions between these substances. This is the case not just with Jiaogulan, but with all other medications and supplements.

Interactions between substances can affect the way that your body processes each individual substance. It can have a positive effect and can be used strategically to greater benefit your body, but it can also have a negative effect on your body. Therefore, it is important to be aware of all potential side effects that come from substance interactions.

Jiaogulan and Prescription Drugs

When we use the word “interaction" it is quite misleading. Drugs combinations do not actually produce chemical reactions inside the human body.

Rather, interactions between a drug, supplement, or food may affect how long a medication stays in the body, often by stimulating or inhibiting the production of specific enzymes in the liver or intestine. These enzymes are part of the cytochrome p450 system, which plays an important role in metabolizing many medications. (1)

Anticoagulant Drugs

Some studies have shown that Jiaogulan may slow down the time it takes for blood to clot. Therefore, people who are taking antiplatelet or anticoagulant drugs should be aware of this potential Jiaogulan side effect.

The interaction between these drugs and Jiaogulan may increase the effect of the given drug. As a result, increased or bruising and/or bleeding could potentially occur. In addition, people who need surgery should also be aware and should stop taking Jiaogulan at least 2 weeks prior to any surgery.

  • Antiplatelets include Plavix and Ticlid
  • Anticoagulants include heparin and warfarin


Jiaogulan can enhance immune system function. As a result, it may alter the effects of immunosuppressants. Anyone taking drugs used to suppress the immune system after organ transplants or in other conditions should be aware of this.

Consuming Jiaogulan is not recommended for patients who take drugs such as:

  • azathioprine (Imuran)
  • CellCept
  • cyclosporine (Neoral, Sandimmune)
  • Prograf
  • Rapamune
  • Zenapak

Jiaogulan & Other Supplements

In theory, because Jiaogulan has the potential to slow your bodies ability to clot blood, it should be taken into consideration when it is used with other herbs that affect blood clotting. (2) Some of the most common herbal products that might inhibit blood clotting are:

  • Danshen
  • Devil’s Claw
  • Eleuthero
  • Garlic
  • Ginger (in high amounts)
  • Ginkgo
  • Horse Chestnut
  • Panax Ginseng
  • Papain

Of course, some interactions can be more severe than others. Jiaogulan side effects are generally found to be minor, but we always recommend being safe rather than sorry.

Therefore, in order to avoid any negative interactions between substances, you should always consult with your doctor and/or pharmacist. They will look at what medications you are currently taking, including any over-the-counter products, vitamins, and herbals. Then, they will be able to give you an informed opinion on whether or not you should be taking Jiaogulan.


  2. Drug Digest

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